Крапивница: синдром или нозологическая единица? Крапивница: современные данные о патогенезе, классификации и терапии
А.А. Чебуркин
Кафедра детских инфекционных болезней ФГБОУ ДПО РМАНПО Минздрава России, Москва, Россия
АЛЛЕРГОЛОГИЯ И ИММУНОЛОГИЯ В ПЕДИАТРИИ, № 3 (54), сентябрь 2018, стр. 4 – 13
DOI: 10.24411/2500-1175-2018-00011
В последние годы было выявлено, что, несмотря на одинаковую клиническую картину, существует широкий спектр подтипов крапивницы, различающихся не только в зависимости от провоцирующих факторов, но и имеющих в основе разные патогенетические механизмы. Термином «крапивница» объединяют группу заболеваний, характеризующихся наличием уртикарной сыпи, ангионевротического отека. Крапивницу следует дифференцировать с болезнями, при которых уртикарная сыпь и ангиоотек являются симптомами основного заболевания, например, уртикарного васкулита, анафилаксии, некоторых аутовоспалительных синдромов, наследственного ангионевротического отека. Основным методом лечения крапивницы в этих случаях является терапия основного заболевания – при этом крапивница является лишь составной его частью – синдромом и исчезает на фоне его ремиссии.При спонтанной крапивницеосновой терапии являются антагонисты H1-рецепторов гистамина (антигистаминные препараты), среди которых, особенно в педиатрической практике, выделяется цетиризин благодаря его специфическим свойствам: он может использоваться с 6-месячного возраста и помимо антигистаминного эффекта установлено его противовоспалительное действие.
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Чебуркин АА. Крапивница: синдром или нозологическая единица? Крапивница: современные данные о патогенезе, классификации и терапии. Аллергология и иммунология в педиатрии. 2018;54(3):4-13. https://doi.org/10.24411/2500-1175-2018-00011
Для корреспонденции
Чебуркин Андрей Андреевич – д.м.н., профессор, профессор кафедры детских инфекционных болезней ФГБОУ ДПО РМАНПО Минздрава России, 125993, г. Москва, ул. Баррикадная, д. 2/1, стр. 1
e-mail: aacaac@yandex.ru.