Clinical-immunological parallels in chronic renal Failure in children
G.A. Makovetskaya, O.V. Borisova, L.I. Mazur, I.V. Barinov
Samara state medical University, Ministry of health of the Russian Federation, Samara, Russia
ALLERGOLOGY AND IMMUNOLOGY IN PEDIATRICS, Volume 61 • Number 2 • June 2020, pp. 41 – 48
DOI: 10.24411/2500-1175-2020-10006
Chronic renal failure (CRF) remains an important problem in childhood. We have studied patients with chronic kidney disease (CKD) at the 3–5 stages at the stages of conservative treatment, dialysis therapy and kidney transplantation (n = 72). The main reason for development is defined CRF in children — CAKUT-syndrome. The main clinical-anamnestic features at different stages of CKD are shown. Clinical-immunological correlations were carried out, hypoimmune state of both cellular and humoral links of immunity was detected in CRF.
- Здравоохранение в России. 2019: Статистический сборник / Росстат. М.: 2019. 170 с.
- KDIGO 2012 Clinical practice guideline for the evaluation and management of chronic kidney disease // Kidney Int. (Suppl.). №3. Р. 41–150.
- Роль некоторых генетических факторов в прогрессировании хронической болезни почек у детей / Г.А. Маковецкая, О.А. Седашкина, Д.В. Печкуров // Практическая медицина. 2015. №7 (92). С.72–76.
- Раннее выявление прогрессирования хронической болезни почек: стандартные и модифицированные методы диагностики / Борисова О.В., Терехин С.С., Маковецкая Г.А., Мазур Л.И., Баринов И.В. // Педиатрия. Журнал им. Г.Н. Сперанского. 2012. Т. 91, № 6. С. 50–54.
- Базовые понятия аллергологии (часть 2) / Грищенко Е.А. // Аллергология и иммунология в педиатрии. 2017. №1 (48). С. 36–48.
- Иммунологические нарушения у пациентов с хронической болезнью почек. Перспективы иммунозаместительной терапии / С.И. Сокуренко, А.Н. Федосеев, Т.В. Борисова // Клиническая практика. 2014. № 3. С. 83–88.
- Other Blood and Immune Disorders in Chronic Kidney Disease /Walter H.Hörl // Comprehensive Clinical Nephrology (Fourth Edition). Р. 959–968. https://doi.org/10.1016/B978-0-323-05876-6.00080-0(дата обращения 05.03.2020).
- IL-10, IL-6, and TNF-alpha: central factors in the altered cytokine network of uremia – the good, the bad, and the ugly / Stenvinkel P., Ketteler M., Johnson R.J., Lindholm B., Pecoits-Filho R., et al // Kidney Int. 2005.67: 1216–1233.
- Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification, and Stratification. Am J Kidney Dis. 2002. T. 2 Suppl. 1. P. 1–246.
- Chronic kidney disease in children / Francesca Becherucci, Rosa Maria Roperto, Marco Materassi, and Paola Romagnani // Clin Kidney J. 2016. № 9 (4). Р. 583–591.
Makovetskaya GA, Borisova OV, Mazur LI, Barinov IV. Clinical-immunological parallels in chronic renal Failure in children. Allergology and Immunology in Pediatrics. 2020;61(2):41-48. (In Russ.) https://doi.org/10.24411/2500-1175-2020-10006
For correspondense
Olga V. Borisova, doctor of medical sciences, professor of the Department of Childhood Infections of Samara State Medical University of the Ministry of Health of the Russian Federation
ORCID: 0000-0003-1430-6708
Address: 89, Chapayevskaya Str., Samara, 443099, Russia
E-mail: olgaborisova74@mail.ru