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Some clinical and laboratory peculiarities in children having private and long disease with monounklosophode syndrome

R.F. Makhmutov 1, T.F. Golubova 2,A.I. Bobrovitskaya 1, V.G. Vorobyeva 3, N.V. Yurinok 1, L.A. Zakharova 1

1 Donetsk National Medical University. M. Gorky, Donetsk, DPR
2 State Scientific and Research Institute of Children’s Balneology, Physiotherapy and Medical Rehabilitation, Evpatoria, Russia
3 Research Institute of Medical Problems of the Family of the Ministry of Health DPR, Donetsk, DPR

ALLERGOLOGY AND IMMUNOLOGY IN PEDIATRICS, Volume 58 • Number 3 • September 2019, pp. 21 – 27
DOI: 10.24411/2500-1175-2019-00013

Abstract

Some clinical and laboratory features of 110 often and long-term ill children (FBD) aged 1 year to 17 years, inclusive, have been studied. Children of the first 3 years of life amounted to 13 (11.8%), preschool age –41 (37.2%) primary school –36 (32.7%) and senior 20 (18.3%). Sexual composition was characterized by a predominance of male children 68 (61.8%).
Depending on the characteristics of the clinical manifestations of the disease, the main group was 78 (70.9%) of often and long-term ill children with a “mononucleosis-like” syndrome; Comparison group – children with frequent and recurrent diseases 32(29.1%) of the same age.
It is established that the formation of frequent and prolonged diseases with “mononucleosis-like” syndrome in children is promoted by the features of premorbid background (violation of posture –62 (79.4%), hypertrophy of palatine tonsils 51 (65.3%), adenoid vegetations–28 (35.8%) and concomitant diseases (astheno- neurotic syndrome –77 (98,7%), vegetative-vascular dysfunction –19 (24,3%), atopic dermatitis –18 (23,0%), dysplastic cardiopathy of secondary genesis –17 (21,7%).The high incidence of syndrome of undifferentiated connective tissue dysplasia in frequently and long-term ill children 17 (21.7%) predisposes to the development in the tonsils inflammation of various etiologies of chronic infection and the formation of the hearth with a “mononucleosis-like” syndrome.

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For citation

Makhmutov RF, Golubova TF, Bobrovitskaya AI, Vorobyeva VG, Yurinok NV, Zakharova LA. Some clinical and laboratory peculiarities in children having private and long disease with monounklosophode syndrome. Allergology and Immunology in Pediatrics. 2019;58(3):21-27. (In Russ.) https://doi.org/10.24411/2500-1175-2019-00013

For correspondense

R.F. Makhmutov
e-mail: ravil@dkt.dn.ua

T.F. Golubova
e-mail: golubovatf@mail.ru

A.I. Bobrovitskaya
e-mail: bobrovickaya38@mail.ru

L.A. Zakharova
e-mail: lubov65@mail.ru

clinical features mononucleosis-like syndrome often and long-term ill children
ALLERGOLOGY and IMMUNOLOGY in PEDIATRICS
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