Food allergies in children, clinical manifestations, proper diet therapy. Clinical cases

T.A. Filatova 1,2, M.G. Ipatova 1,2, Y.G. Muhina 1, N.N. Taran 1,3, E.A. Antonova 1

1 Pirogov Russian National Research Medical University, Moscow, Russia
2 Filatov Moscow City Pediatric Clinic № 13, Moscow, Russia
3 Research Institute of Nutrition, Moscow, Russia

ALLERGOLOGY AND IMMUNOLOGY IN PEDIATRICS, Volume 55 • Number 4 • December 2018, pp. 18 – 24
DOI: 10.24411/2500-1175-2018-00018

Allergic diseases are global public health problem. Food allergy is the most complicated condition from all allergic diseases. Nutrition is the main factor determining the development and state of the children’s health. For normal development of children require a balanced diet that contains sufficient amount of protein, fat, carbohydrates, vitamins and minerals. In children with food allergy, the main treatment is a strict elimination diet with the exclusion from the diet cause significant products, which can lead to the development of nutritional deficiency and deficient states of varying severity. This article describes two clinical cases of children with FA and nutritional deficiency on the background of improper supervision, lack of proper elimination diet, with right compensation and subsidy of clinical nutrition.

  1. World Health Organisation: Global surveillance, prevention, and control of chronic respiratory diseases: a comprehensive approach; 2007. gard/publications/GARD Book 2007.pdf
  2. The prevalence of food allergy: a meta-analysis / R.J. Rona, T. Keil, C. Summers et al. // J. Allergy Clin. Immunol. 2007. Vol. 120, № 3. P. 638–646.
  3. World Allergy organization (WAO) diagnosis and rationale for action against Cow’s milk allergy (DRACMA) guidelines / A. Fiocchi, J. Brozek, H. Schunemann et al. // World Allergy Organ. J. 2010. Vol. 3, № 4. 57–161.
  4. Prevalence and cumulative incidence of food hypersensitivity in the first 3 years of life / C. Venter, B. Pereira, K. Voigt et al. // Allergy. 2008. Vol. 63, № P. 354–359.
  5. De Boissieu D., Dupont C. Allergy to extensively hydrolysed cows’ milk proteins in infants: safety and duration of amino acid-based formula // J. Pediatr., 2002. Vol. 141. P. 271–273.
  6. Prosser C., McLaren G., Rutherfurd R. Digestion of milk proteins from cow or goat milk infant formula / Poster paper presented at the 11th Asian Congress of Paediatrics. Bangkok, Thailand, 2003. P. 2–7.
  7. Monaci L., Tregoat V., van Hengel A.J. Milk allergens, their characteristics and their detection in food: A review // Eur. Food Res. Technol. 2006. Vol. 223. P. 149–179.
  8. Is the use of goat’s milk justified in infants with cow’s milk protein allergy? / A.N. Pampura, T.E. Borovik, I. Zakharova et al. // Ros. Vestn. Perinatol. Pediatr. 2012. Vol. 4, № 1. 139–146.
  9. A practical approach to vitamin and mineral supplementation in food allergic children / R. Meyer, C. de Koker, R. Dziubak et al. // Clinical and Translational Allergy. 2015. № 5. P. 11.
  10. Нутритивный статус детей с пищевой аллергией / О.Н. Титова, Н.Н. Таран, Т.В. Строкова и др. // Российский вестник перинатологии и педиатрии.  Инновационные технологии в педиатрии и детской хирургии. 2016. Т. 61, № 4. С. 156.
  11. Протокол ведения детей с аллергией к белкам коровьего молока / под ред. А.А. Баранова, Л.С. Намазовой-Барановой, С.Г. Макаровой. М.: ПедиатрЪ, 2016. 48 с.
  12. Нутритивная недостаточность и принципы ее коррекции у детей с пищевой аллергией. Разбор клинических случаев / М.Г. Ипатова, Т.А. Филатова, Е.А. Антонова и др. // Эффективная фармакотерапия. Педиатрия. 2018. № 1 (14),
  13. Milk-induced pulmonary disease in infants (Heiner syndrome) / I. Moissidis, D. Chaidaroon, P. Vichyanond et al. // Pediatr. Allergy Immunol. 2005. Sept. Vol. 16, № 6. P. 545–52.
  14. Sorensen K., Fry C., Allford A. et al. Longitudinal study shows improved nutrient intakes and growth with an amino acid formula for children ≥1y with cow’s milk allergy and related conditions // Abstracts from the European Academy of Allergy and Clinical Immunology Congress, 17–21 June 2017, Helsinki, Finland; Vol. 72, Issue S103.

Filatova TA, Ipatova MG, Muhina YG, Taran NN, Antonova EA. Food allergies in children, clinical manifestations, proper diet therapy. Clinical cases. Allergology and Immunology in Pediatrics. 2018;55(4):18-24. (In Russ.)

For correspondense

T.A. Filatova