Severy skin reactions at drug allergy

D.Sh. Macharadze 1, Y.G. Khaliulin 1,2, B.G. Kulumbegov 3

1 Peoples’ Friendship University of Russia, Moscow, Russia
2 JSC European Medical Center, Moscow, Russia
3 Center of Allergy and Immunology, Tbilisi, Georgia

ALLERGOLOGY AND IMMUNOLOGY IN PEDIATRICS, Volume 56 • Number 1 • March 2019, pp. 4 – 10
DOI: 10.24411/2500-1175-2019-00001

The skin is one of the organs most often involved in adverse drug reactions. Most cases of rash caused by medication are not dangerous, but six of them pose a high risk for a patient’s life. They should be recognized at an early stage of development and quickly take measures to prevent severe complications. The article presents a brief overview of the clinical manifestations, treatment and prognosis of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) or Lyell’s syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis and drug-induced bullous pemphigoid.

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Macharadze DSh, Khaliulin YG, Kulumbegov BG. Severy skin reactions at drug allergy. Allergology and Immunology in Pediatrics. 2019;56(1):4-10. (In Russ.)

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D.Sh. Macharadze


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