Obvious and hidden ways of sensitization for children with food allergies and atopic dermatitis

T.S. Lepeshkova¹, E.V. Andronova², L.R. Zakirova¹

¹Federal State Budgetary Educational Institution of Higher Professional Education «The Urals State Medical University» of the Ministry of Health of Russia, Ekaterinburg, Russia;
²«Semeynuy Doctor», Magnitogorsk, Russia

ALLERGOLOGY AND IMMUNOLOGY IN PEDIATRICS, Volume 65 • Number 2 • June 2021, pp. 25-30
DOI: 10.24412/2500-1175-2021-2-25-30

Abstract

Recent decades see a steady increase in the number of patients suffering from food allergies worldwide. Children have a variety of clinical symptoms of food allergy. Some patients have local allergic reaction in the oral cavity, other — atopic dermatitis or gastrointestinal allergy, and sometimes there is the food anaphylaxis that put child’s life in danger. Atopic dermatitis is among the most common food allergy symptom. We all know that atopic dermatitis is a multifactorial chronic disease characterized by skin itching and inflammation. Allergens in children food intake are considered to be the main factors to provoke atopic dermatitis at an early age, but sometimes not only oral allergens are the main triggers of the disease. Nowadays we get more data about inhalation and transdermal ways of sensitization with atopic dermatitis.
Resent global scientific discoveries in molecular allergology changed the awareness of allergen structure and new ways to detect allergy. Scientists proved the direct connection between recurrent and difficult to treat signs of atopic dermatitis and IgE-dependent allergic reactions. That forces doctors to choose ISAC-112 ImmunoCAP test to treat patients with severe skin lesions to clarify the spectrum of sensitization.
Objective: to describe a clinical case and to stress the importance of clarifying all possible allergens that can sensitize a patient with symptoms of atopic dermatitis, detected by ISAC-112 ImmunoCAP test.

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Lepeshkova TS, Andronova EV, Zakirova LR. Obvious and hidden ways of sensitization for children with food allergies and atopic dermatitis. Allergology and Immunology in Pediatrics. 2021;2(65):25–30. (In Russ.) https://doi.org/10.24412/2500-1175-2021-2-25-30

For correspondense

Tatiana S. Lepeshkova, candidate of medical sciences, associate Professor Department of polyclinic Pediatrics and Pediatrics faculty of advanced training and retraining of Ural State Medical University of the Ministry of Health of the RF
ORCID: 0000-0002-0716-3529
Address: Repina str., aр. 3, Ekaterinburg, 620028, Russia
E-mail: levlpa@mail.ru