Features of clinical course and skin lesions associated with new coronavirus infection in children


Volume 68 • Issue 1 • March 2022, pp. 27-33

Received: 11.12.2021​ | Accepted for publication: 30.12.2021 | ​Publication date: 21.03.2022

ORCID logo I.A. Plotnikova1 ORCID logo V.L. Zelentsova1 I.G. Lavrik2 , A.A. Egorov1 S.A. Nakhratova1

1 Department of Childhood Diseases, Faculty of Treatment and Prevention, Ural State Medical University;
2 State Autonomous Healthcare Institution of the Sverdlovsk Region “Children’s City Clinical Hospital № 9”;

Full text PDF (rus)

This article discusses the features of skin lesions and the clinical course of a new coronavirus infection in children. Among the extrapulmonary signs associated with COVID-19, dermatologic manifestations have increasingly appeared in the past few months. The aim of the study was to correlate available data in the literature on variants of dermatological manifestations of COVID-19 in children with clinical examples of skin lesions associated with this infection in patients seen by a specialized dermatologist. We used PubMed and Cyberleninka search engines for the period 2020–2021 Systematized variants of dermatological syndromes in children who had undergone COVID-19 described in reviews of materials by domestic and foreign researchers. The authors analyzed the primary medical records and photographic archives of children admitted to the outpatient clinic of a dermatologist at Yekaterinburg municipal clinical hospital No. 9 for 1 month after the established family contact with a new case of coronavirus infection. Analysis of scientific literature data showed that SARS-CoV-2 virus-associated skin lesions in children were more frequent in the mild course of infection, presumably with the implementation of an immunocomplex mechanism of vascular and epithelial damage. The pronounced vascular damage is a distinctive feature of COVID-19-related exanthemas, especially when localized on the fingers of the lower extremities. This article presents 5 clinical cases of children with various forms of acute dermatoses: urticaria, frostbite-like exanthema of the fingers, onychodystrophy, alopecia, and generalized pustular psoriasis of Zumbush. Only three children had laboratory confirmation of SARS-CoV-2 infection.


1. Vremennye metodicheskie rekomendatsii. Profilaktika, diagnostika i lechenie novoi koronavirusnoi infektsii (COVID-19). Versiya 12 (utv. Minzdravom Rossii 21.09.2021). (in Russ.)

2. WHO Coronavirus (COVID-19) Dashboard [electronic resource]. URL: https://covid19.who.int/ (дата обращения 07.10.2021).

3. Namazova-Baranova LS, Baranov AA. COVID-19 i deti. Pul’monologiya. 2020; 30(5): 609–628. (in Russ.) doi:10.18093/0869-0189-2020-30-5-609-628.

4. Metodicheskie rekomendatsii «Osobennosti klinicheskikh proyavlenii i lecheniya zabolevaniya, vyzvannogo novoi koronavirusnoi infektsiei (COVID-19) u detei». Versiya 2 (utv. Minzdravom Rossii 03.07.2020). (in Russ.)

5. Melekhina EV, Gorelov AV, Muzyka AD. Klinicheskie osobennosti techeniya COVID-19 u detei razlichnykh vozrastnykh grupp. Obzor literatury k nachalu aprelya 2020 goda. Voprosy prakticheskoi pediatrii. 2020; 15(2): 7–20. (in Russ.) doi:10.20953/1817-7646-2020-2-7-20.

6. Rusinova DS, Nikonov EL, Namazova-Baranova LS, Glazkova GP, Vishneva EA, Kaitukova EV, Privalova TE. Pervye rezul’taty nablyudeniya za det’mi, perebolevshimi COVID-19 v Moskve. Pediatricheskaya farmakologiya. 2020; 17(2): 95–102. (in Russ.) doi:10.15690/pf.v17i2.2095).

7. Genovese G, Moltrasio C, Berti E, Marzano AV. Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives. Dermatology. 2021; 237(1): 1–12. doi:10.1159/000512932.

8. Gkoutzourelas A, Bogdanos DP, Sakkas LI. Kawasaki Disease and COVID-19. Mediterr J Rheumatol. 2020 Sep; 31(Suppl 2): 268–274. doi:10.31138/mjr.31.3.268.

9. Andina D, Belloni-Fortina A, Bodemer C, Bonifazi E, Chiriac A, Colmenero I, et al. Skin manifestations of COVID-19 in children: Part 3. Clin Exp Dermatol. 2021 Apr; 46(3): 462–472. doi:10.1111/ced.14483.


Plotnikova IA, Zelentsova VL, Lavrik IG, Egorov AA, Nakhratova SA. Allergology and Immunology in Pediatrics. 2022;1:27-33 (In Russ.) https://doi.org/10.53529/2500-1175-2022-1-27-33

For correspondence:

Inga A. Plotnikova

doctor of medical sciences, assistant professor of Department of Childhood Diseases, Faculty of Treatment and Prevention of the Ural State Medical University

ORCID logo   0000-0002-6909-1487
map marker alt icon   3 Repin Str., Yekaterinburg, 620028, Russia
smt1 email icon   inga63@bk.ru

Supporting agencies:

There is no source of funding

Сonflict of interest::

no conflict of interest